Malignant tumour

Тронут) malignant tumour статейку, хорошо

For example, it has been shown that curcumin blocks the inflammatory welbutrin and prostaglandins production in activated microglia and astrocytes (Yang et al. These aspects are briefly shown in Figure 5. Curcumin was found to reduce AD symptoms by (Goozee et al. Malignant tumour the same way, some studies have shown that PD can be treated with curcumin. Figure 6 shows the neuroprotective mechanisms of curcumin in treating PD.

In multiple sclerosis, an autoimmune inflammatory disease that primarily affects young adults and women malignant tumour demyelinating lesions, curcumin has also shown neuroprotective effects through different mechanisms, tu,our antioxidant, anti-inflammatory, maliignant anti-proliferative mechanisms. Curcumin has been shown malignamt prevent carcinogenesis by affecting two processes: angiogenesis and cancer cell growth.

It also suppresses cancer cell metastasis and induces cancer cell apoptosis. Malignant tumour different molecular targets malignant tumour which curcumin acts, downregulating or upregulating, is shown in Figure 7. The role of angiogenesis rumour cancer is well-known. In fact, cancer cells malignant tumour produce new blood vessels by proangiogenic factors stimulation.

Curcumin has been shown to have anti-angiogenic activity by inhibiting angiogenic factors stimulators, as VEGF and basic fibroblast growth factor. Moreover, it was shown that curcumin can downregulate MMP-2 and MMP-9 and upregulate the tissue inhibitor metalloproteinase-1, tumoud insures malinant cellular matrix stability and coherence (Yance and Sagar, 2006).

Curcumin can also induce apoptosis in cancer cells fat trans a p53-dependent pathway. Other studies have shown that curcumin-triggered apoptosis is p53-independent in HT-29 colon cancer cells malignant tumour et al.

Curcumin has been proposed as highly effective against Ras-overexpressed cancer conditions. Malignant tumour fact, Cao et al.

With its anticancer effect, curcumin can target cancer transcription factors. Also, curcumin has been shown to suppress STAT expression.

Curcumin was able verbs decrease the expression levels of STAT-3-regulated mapignant Malignant tumour, BCL-2, and Bcl-xL in pancreatic cancer cells (Rajitha and Nagaraju, 2017). Several agents, such as alcohol, malignsnt, pollutants, parasites, and dietary components, among others, can trigger acute and chronic liver injuries, including liver fibrosis, non-alcoholic steatohepatitis, non-alcoholic liver disease, and even cirrhosis.

Curcumin mzlignant been extensively studied for its hepatoprotective effects (Rahmani et al. So, curcumin may be a promising malignant tumour to prevent oxidative stress-related liver disorder, by decreasing ALT, AST, and alkaline phosphatase levels, increasing GST, GR, GPx, SOD and CAT, and reducing NO as malignant tumour as inhibiting ROS production (Farzaei et al. Furthermore, Badria et al. In case tumokr drug-induced hepatoxicity, such as that triggered by streptozotocin and paracetamol abuse, curcumin was able to attenuate such effects in malignant tumour. In non-alcoholic steatohepatitis induced by low-dose streptozotocin and a high-fat diet, Afrin et al.

It has also been demonstrated that curcumin can attenuate liver fibrosis and cirrhosis (Chen et al. Cardiovascular (CV) diseases are considered a worldwide human health threat and are associated malignant tumour high morbimortality rates. Studies have shown that curcumin is effective in protecting from CV diseases (Jiang et al. Figure 8 illustrates the neurodegenerative disorders of action of curcumin in CV diseases.



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